Many readers will doubtless be astonished to learn that animals were being fired aloft in U.S. and Soviet research rockets in the late 1940s. In fact most people not only believe that the Russian space dog Laika was the first canine to be launched into space, but also that the high-profile, precursory Mercury flights of chimps Ham and Enos were the only primate flights conducted by the United States. In fact, both countries had sent literally dozens of animals aloft for many years prior to these events and continued to do so for many years after. Other latter-day space nations, such as France and China, would also begin to use animals in their own space research.
Animals in Space will explain why dogs, primates, mice and other rodents were chosen and tested, at a time when dedicated scientists from both space nations were determined to establish the survivability of human subjects on both ballistic and orbital space flights. It will also recount the way this happened; the secrecy involved and the methods employed, and offer an objective analysis of how the role of animals as spaceflight test subjects not only evolved, but subsequently changed over the years in response to a public outcry led by animal activists. It will explore the ways in which animal high-altitude and space flight research impacted on space flight biomedicine and technology, and how the results - both successful and disappointing - allowed human beings to then undertake that same hazardous journey with far greater understanding and confidence.
This book is intended as a detailed yet highly readable and balanced account of the history of animal space flights, and the resultant application of hard-won research to space technology and astrobiology. It will undoubtedly become the ultimate authority on animal space flights.
This book provides insight into the Life Cycle Management (LCM) concept and the progress in its implementation. LCM is a management concept applied in industrial and service sectors to improve products and services, while enhancing the overall sustainability performance of business and its value chains. In this regard, LCM is an opportunity to differentiate through sustainability performance on the market place, working with all departments of a company such as research and development, procurement and marketing, and to enhance the collaboration with stakeholders along a company's value chain. LCM is used beyond short-term business success and aims at long-term achievements by minimizing environmental and socio-economic burden, while maximizing economic and social value.
The IT community has always struggled with questions concerning the value of an organization's investment in software and hardware. It is the goal of value-based software engineering (VBSE) to develop models and measures of value which are of use for managers, developers and users as they make tradeoff decisions between, for example, quality and cost or functionality and schedule - such decisions must be economically feasible and comprehensible to the stakeholders with differing value perspectives. VBSE has its roots in work on software engineering economics, pioneered by Barry Boehm in the early 1980s. However, the emergence of a wider scope that defines VBSE is more recent. VBSE extends the merely technical ISO software engineering definition with elements not only from economics, but also from cognitive science, finance, management science, behavioral sciences, and decision sciences, giving rise to a truly multi-disciplinary framework.
Biffl and his co-editors invited leading researchers and structured their contributions into three parts, following an introduction into the area by Boehm himself. They first detail the foundations of VBSE, followed by a presentation of state-of-the-art methods and techniques. The third part demonstrates the benefits of VBSE through concrete examples and case studies.
This book deviates from the more anecdotal style of many management-oriented software engineering books and so appeals particularly to all readers who are interested in solid foundations for high-level aspects of software engineering decision making, i.e., to product or project managers driven by economics and to software engineering researchers and students.
This book offers a wide-ranging and up-to-date overview of the basic science underlying PET and
its preclinical and clinical applications in modern medicine. In addition, it provides the reader with a sound understanding of the scientific principles and use of PET in routine practice and biomedical imaging research. The opening sections address the fundamental physics, radiation safety, CT scanning dosimetry, and dosimetry of PET radiotracers, chemistry and regulation of PET radiopharmaceuticals, with information on labeling strategies, tracer quality control, and regulation of radiopharmaceutical production in Europe and the United States. PET physics and instrumentation are then discussed, covering the basic principles of PET and PET scanning systems, hybrid PET/CT and PET/MR imaging, system calibration, acceptance testing, and quality control. Subsequent sections focus on image reconstruction, processing, and quantitation in PET and hybrid PET and on imaging artifacts and correction techniques, with particular attention to partial volume correction and motion artifacts. The book closes by examining clinical applications of PET and hybrid PET and their physiological and/or molecular basis in conjunction with technical foundations in the disciplines of oncology, cardiology and neurology, PET in pediatric malignancy and its role in radiotherapy treatment planning. Basic Science of PET Imaging will meet the needs of nuclear medicine practitioners, other radiology specialists, and trainees in these fields.
Das blaue Buch" der Psychosen-Ratgeber von Josef Bäuml komplett neu bearbeitet
Das Auftreten einer psychotischen Erkrankung führt immer wieder zu Sprachlosigkeit und Verunsicherung. Warum erkrankt jemand überhaupt an Schizophrenie? Welche Konsequenzen hat dies für das Leben von Patienten und Angehrigen? Welche Therapiemglichkeiten gibt es?
Hier finden Sie die Antworten auf alle Ihre drängenden Fragen. Der Ratgeber legt besonderen Wert auf die Erläuterung der medikamentsen Therapie, ihrer Notwendigkeit und ihre Verknüpfung mit anderen Therapien.
Einfach und verständlich geschrieben, ist das Buch ein unentbehrlicher Ratgeber für alle, die sich mit dieser Gruppe von Erkrankungen auseinander setzen müssen. Zudem dient er auch als Leitfaden für Gespräche mit professionellen Helfern.
Neu in dieser Auflage:
Alle wichtigen aktuellen Therapieentwicklungen der letzten Jahre
Übersicht über die neuesten Erkenntnisse bezüglich der Ursachen von Psychosen
Environmental chemistry is a fast developing science aimed at deciphering fundamental mechanisms ruling the behaviour of pollutants in ecosystems. Applying this knowledge to current environmental issues leads to the remediation of environmental media, and to new, low energy, low emission, sustainable processes. Chapters review analysis and remediation of pollutants such as greenhouse gases, chiral pharmaceuticals, dyes, chlorinated organics, arsenic, toxic metals and pathogen in air, water, plant and soil. Several highlights include the overlooked impact of air pollutants from buildings for health risk, innovative remediation techniques such as bioreactors for gas treatment, electrochemical cleaning of pharmaceuticals, sequestration on Fe-Mn nodules, phytoremediation and photocatalytical inactivation of microbial pathogens. This book will be a valuable source of information for engineers and students developing novel applied techniques to monitor and clean pollutants in air, wastewater, soils and sediments.
This book includes the texts of the survey lectures given by plenary speakers at the 11th International ISAAC Congress held in Växj, Sweden, on 14-18 August, 2017. It is the purpose of ISAAC to promote analysis, its applications, and its interaction with computation. Analysis is understood here in the broad sense of the word, including differential equations, integral equations, functional analysis, and function theory. With this objective, ISAAC organizes international Congresses for the presentation and discussion of research on analysis.
The plenary lectures in the present volume, authored by eminent specialists, are devoted to some exciting recent developments, topics including: local solvability for subprincipal type operators; fractional-order Laplacians; degenerate complex vector fields in the plane; lower bounds for pseudo-differential operators; a survey on Morrey spaces; localization operators in Signal Theory and Quantum Mechanics. Thanks to theaccessible style used, readers only need a basic command of Calculus.
This book will appeal to scientists, teachers, and graduate students in Mathematics, in particular Mathematical Analysis, Probability and Statistics, Numerical Analysis and Mathematical Physics.
The Third Edition of Handbook of Evidence-Based Radiation Oncology updates and revises the previous successful editions and serves as a key reference for radiation oncology professionals. Organized by body site, concise clinical chapters provide easy access to critical information. Important "pearls" of epidemiology, anatomy, pathology, and clinical presentation are highlighted. The key elements of the work-up are listed, followed by staging and/or risk classification systems. Treatment recommendations are discussed based on stage, histology, and/or risk classification. Brief summaries of key trials and studies provide the rationale for the recommendations. Practical guidelines for radiation techniques are described and complications and follow-up guidelines are outlined. The Third Edition incorporates new key studies and trials to reflect current radiation oncology practice; includes the most recent staging systems; and features new color illustrations and anatomic atlases to aid in treatment planning. This book is a valuable resource for students, resident physicians, fellows, and other practitioners of radiation oncology.
This book expands on the classical statistical multivariate analysis theory by focusing on bilinear regression models, a class of models comprising the classical growth curve model and its extensions. In order to analyze the bilinear regression models in an interpretable way, concepts from linear models are extended and applied to tensor spaces. Further, the book considers decompositions of tensor products into natural subspaces, and addresses maximum likelihood estimation, residual analysis, influential observation analysis and testing hypotheses, where properties of estimators such as moments, asymptotic distributions or approximations of distributions are also studied. Throughout the text, examples and several analyzed data sets illustrate the different approaches, and fresh insights into classical multivariate analysis are provided. This monograph is of interest to researchers and Ph.D. students in mathematical statistics, signal processing and other fields where statistical multivariate analysis is utilized. It can also be used as a text for second graduate-level courses on multivariate analysis.
The New Mathematical Coloring Book (TNMCB) includes striking results of the past 15-year renaissance that produced new approaches, advances, and solutions to problems from the first edition. A large part of the new edition "Ask what your computer can do for you," presents the recent breakthrough by Aubrey de Grey and works by Marijn Heule, Jaan Parts, Geoffrey Exoo, and Dan Ismailescu. TNMCB introduces new open problems and conjectures that will pave the way to the future keeping the book in the center of the field. TNMCB presents mathematics of coloring as an evolution of ideas, with biographies of their creators and historical setting of the world around them, and the world around us.
A new thing in the world at the time, TMCB I is now joined by a colossal sibling containing more than twice as much of what only Alexander Soifer can deliver: an interweaving of mathematics with history and biography, well-seasoned with controversy and opinion. -Peter D. Johnson, Jr.Auburn University
Like TMCB I, TMCB II is a unique combination of Mathematics, History, and Biography written by a skilled journalist who has been intimately involved with the story for the last half-century. ...The nature of the subject makes much of the material accessible to students, but also of interest to working Mathematicians. ... In addition to learning some wonderful Mathematics, students will learn to appreciate the influences of Paul Erdos, Ron Graham, and others.-Geoffrey ExooIndiana State University
The beautiful and unique Mathematical coloring book of Alexander Soifer is another case of "good mathematics", containing a lot of similar examples (it is not by chance that Szemerédi's Theorem story is included as well) and presenting mathematics as both a science and an art...-Peter MihókMathematical Reviews, MathSciNet
A postman came to the door with a copy of the masterpiece of the century. I thank you and the mathematics community should thank you for years to come. You have set a standard for writing about mathematics and mathematicians that will be hard to match.- Harold W. KuhnPrinceton University
I have never encountered a book of this kind. The best description of it I can give is that it is a mystery novel... I found it hard to stop reading before I finished (in two days) the whole text. Soifer engages the reader's attention not only mathematically, but emotionally and esthetically. May you enjoy the book as much as I did!- Branko GrünbaumUniversity of Washington
I am in absolute awe of your 2008 book.
-Aubrey D.N.J. de GreyLEV Foundation
This volume addresses the gap in knowledge around generative AI and its applications in education. It draws on the recent history of technological innovation and digital pedagogies, locating generative AI in the contemporary discourse around education futures. It argues that a new hybrid model of education is emerging, requiring educational institutions to embed generative AI into course and programme design, delivery and assessment. It also proposes a shift from a focus on learning as output to learning as a process, and explores what that shift might look like. Grounded in educational theory, it offers actionable pedagogy-informed guidance on how to position AI as a collaborator in the construction of learning in a manner that is congruent with the values and aims of education. It offers advice based on evidence-based digital pedagogy, including frameworks for effective teaching and learning with generative AI, that enable educators and designers to put these ideas into practice.
The book also explores the wider context informing this shift, connecting narratives from governments and industry leaders on the strategic importance of generative AI and lifelong learning, learning agility, and future skills that make the case for the integration of competency-based assessment into mainstream education. Finally, going beyond pedagogy and practice, it considers of some of the broader issues, including limitations and ethics, and the implications of integrating generative AI into institutional planning and design, and includes a sample roadmap for education leaders to start the process of integrating generative AI into their institutions.
This work approaches the topic of generative AI from the vantage point of educators by addressing themes and concerns that will resonate with professionals in the sector.
Embark on a journey through the dynamic landscape of global financial crime combating with our latest collection, meticulously curated by leading researchers. At the intersection of finance, technology, law, governance, and international cooperation, this multidisciplinary exploration offers profound insights into the nuanced world of financial crime across diverse jurisdictions, including Australia, Germany, New Zealand, Nigeria and the United Kingdom.
Discover a wealth of knowledge as contributors investigate facets such as asset forfeiture, non-conviction-based asset recovery, money laundering in the real estate sector, and the challenges and opportunities posed by new technologies and fintechs. Unravel the crypto crime and terror nexus and explore the necessity of public-private collaboration to combat the abuse of Non-Fungible Tokens. Dive into policy approaches, including the WireCard scandal, and understand how good governance, both public and corporate, remains paramount in the fight against financial crime.
As we navigate an age of intergovernmental rulemaking, the collection emphasizes the crucial role of robust governance frameworks and examines the impact of permissive regulation on practices in the City of London. Delve into discussions on crime risk, risk management, de-risking, and the potential consequences of overcompliance and conservative risk approaches on financial exclusion levels.
While global standards on financial crime have solidified over the past three decades, the future direction of standard-setting and compliance enforcement remains uncertain in our complex global political landscape. The collection concludes by pondering these current challenges, offering a thought-provoking exploration of what lies ahead.
This collection a product of the Financial Integrity Hub (FIH), serves as a valuable resource for financial regulators, compliance officers, and scholars, offering profound insights and perspectives to navigate the dynamic landscape of financial crime combatting.
Chapters "Non-Conviction-Based Asset Recovery in Nigeria - An Additional Tool for Law Enforcement Agencies?", "'De-risking' Denials of Bank Services: An Over-Compliance Dilemma?" and "Terror on the Blockchain: The Emergent Crypto-Crime-Terror Nexus" are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
This volume is the first manual book to address fire-cracked rock (FCR) or fire-affected rock analysis, thus filling a significant gap in the market and in the existing literature. This book develops a method and theory for how FCR was used, to familiarize readers with a new approach to FCR analysis. The book provides a history and background of fire-cracked rock and leads the reader through the entire process of identifying, categorizing, and analyzing FCR and related features, from the first steps through to interpretations of function, use-alteration, fracturing patterns, experimentation, ethnographic/ethnohistoric uses, and so forth. In addition to exploring the fundamentals of FCR analysis, the book will also cover new and cutting-edge techniques.
This manual is designed to walk archaeologists from step one of FCR analysis to final advanced interpretations of use. It is meant to serve as a laboratory and field guide for students and professionals, containing illustrations, photographs, and case studies in order to familiarize readers with the identification and analysis process while also providing a theoretical and methodological guide for advance academic and cultural resource management research. Thus, this book is meant to target a wide global audience and spatiotemporal range, spanning hundreds of millennia of the human experience, from paleoanthropology and the early adoption of fire through to the present.
Where FCR was once simply quantified according to weight and size, this book will transform it into a significant diagnostic artifact in the study of ancient foodways and domestic life. At sites where organic preservation is poor to non-existent, and the quotidian sphere is obscure, the use of FCR to determine cooking methods and everyday life will come as a breakthrough. This will be a pioneering manual for the study of FCR, focusing on the ways practicing archaeologists can infer function from their FCR collections.
This book discusses the living conditions and resulting political attitudes and participation patterns of young people, especially in the countries of the "Global East"-regions of the world that have so far received little public attention-and which subjects growing up in these countries to an in-depth analysis. Today's youth is coming of age in a climate of social disparity and heterogeneous living circumstances. Amid the economic and political uncertainty in many of the world's crisis countries, adolescents are faced with a multiplicity of challenges which may manifest in social exclusion, unequal access to education, and high youth unemployment rates. The political circumstances from which these effects arise are varied in nature and include attempts at democratization and repressive tendencies in Arab states, financial crises in Southern Europe, and the growing alienation of South-Eastern Europe and the countries of the former Soviet Union from the European Union as a result of disappointed expectations.
The empirical data basis of the individual articles is provided by current country-specific youth studies. The book is divided into three sections. Part One outlines the differences in the economic and political status of young people in selected countries. Part Two focuses on the political and social involvement of adolescents. Finally, Part Three discusses adolescents' responses to the situations in their home countries. A detailed presentation of the political behavior of young people in crisis countries, this book will be useful to students and researchers interested in political science, public participation, youth welfare, education, and social work.
This volume in the Subcellular Biochemistry (SCBI) series is a continuation of several previous volumes devoted to the structural and functional study of protein complexes. The expanding nature of this field of study, derived mainly from X-ray crystallography and electron cryomicroscopy, justifies the continuing expansion of coverage in an almost encyclopaedic manner within the SCBI series.
Experienced and active researchers in the field shed light on the biology of protein complexes involved in important cellular functions from different perspectives, such as AcrAB-TolC, and CST. Other topics covered are: the Toxin-Antitoxin systems in cell survival, the role of the ATPases CueR and RUVBL1-RUVBL2 in the regulation of gene expression, complexes with multiple functions in the cell such as VCP/p97 or the Vault complex, FtsA and FtsZ in bacterial cell division, GATOR1 and GATOR2 in amino acid sensing, TRPA1 and the Serotonin Transporter in signaling, oligomeric structures in eukaryotic cells such as amyloids and invertases, among others.
The book is richly illustrated, the result of an impressive integration of structural data from X-ray crystallography and cryo-electron microscopy. Functional aspects of protein-protein interactions are also featured prominently, providing a valuable contribution for researchers and scholars.
Chapter 13 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
This book reflects on 8 decades of research on one of the longest-standing unsolved problems in modern astrophysics: why does the Sun form a hot corona? The authors give a critical overview of the field and offer suggestions on how to bridge the chasm between what we can measure, and what we can calculate. They go back to basics to explain why the problem is difficult, where we have made progress and where we have not, to help the next generation of scientists devise novel techniques to crack such a long-lasting problem. A way forward is formulated centered around refutation, using Bayesian methods to propose and to try to reject hypotheses and models, and avoiding seduction by ``confirmation bias''.This book is aimed at physicists, students and researchers interested in understanding, learning from and solving the coronal heating problem, in an era of new dedicated facilities such as the Parker Solar Probe and the Daniel K. Inouye Solar Telescope.
Thebook will appeal to those interested in understanding research methods and how they are changing in the modern academic environment, particular in astrophysics and Earth sciences where remote sensing is essential.
This book aims to integrate multiple disciplinary such as management, economics, and geography from the perspective of resource science and also to strengthen research on resource management to promote sustainability in natural resources. It established clear definition of natural resources and in-depth exploration of main fields such as water resources, land resources, and agricultural resources. Classic methods of economics are applied to solve the problems of resource consumption, environmental pollution, and climate change in modern society. On the basis of classical economics, the disciplinary system of environmental and natural resources is further developed. It is a helpful reference for readers to further study natural resources and environmental economics.
This book analyzes the political economy governing energy regulation across the African continent. Presenting case studies that span diverse energy sectors and countries, it provides an overview of their complex political and regulatory frameworks. The book explores emerging technologies and energy markets, highlighting Africa's preparedness for the energy transition, and sheds light on the pivotal role of cross-border energy trade with regard to energy access. Further, it examines regulators' influence within regional power pools, as well as their contribution to gender mainstreaming in the energy sector, addressing vital social issues. This book is divided into five parts, the first of which focuses on the political economy of energy regulation. The second part discusses emerging technologies and climate change issues, while the third examines regional energy markets, and regional institutional collaboration. The fourth part features contributions on gender mainstreaming, while part five rounds up the coverage. The book will be of interest to policymakers and investors in Africa, as well as scholars interested in energy regulation and economics.
This book provides a comprehensive understanding of the challenges being faced in managing plastic waste and showcases innovative solutions that can mitigate the adverse effects of plastic pollution on the environment. This timely book brings together a multi-disciplinary group of experts to outline the scale and complexity of the plastics pollution issue while advancing innovative and inclusive solutions. Spanning perspectives from policy, industry, advocacy, technology, and academia, the book provides a comprehensive understanding of plastic waste sources, impacts, and management approaches. Policymakers, municipal authorities, industry leaders, entrepreneurs, researchers, students, advocates and informed citizens seeking to drive progress on sustainable plastic waste management will find crucial insights and inspirational models in this book.
This groundbreaking book delves deep into the history of AI, the major techniques and algorithms of machine learning and deep learning, and the critical role of data sources and processing in these disciplines. It covers a range of AI applications in human geography, including population distribution, land use, environmental risk assessment, and socioeconomic analysis. In urban planning, the book explores AI-driven approaches to smart cities, transportation management, urban growth prediction, and sustainable development, among others.
As AI continues to permeate every aspect of human life, it is essential to understand and address the ethical considerations and challenges associated with AI-driven planning. This book tackles crucial issues such as data privacy, algorithmic bias, equitable access to technology, and the future of employment in the fields of geography and urban planning. In addition, it presents inspiring case studies, highlighting successful AI applications in human geography and urban planning, and offers insights into future research directions and challenges.
This book is a must-read for students, researchers, and professionals in geography, urban planning, environmental studies, and related fields. It is also an invaluable resource for policymakers and urban planners seeking to leverage the power of AI to create smarter, more sustainable, and equitable cities and communities. This book equips you with the knowledge and tools to harness the potential of AI, leading the way to a better understanding of our world and a brighter future for all.
This book provides a detailed overview of mosquitoes. It covers aspects of their origin, evolution, morphology, diversity, biology, and host finding and recognition. It also describes the behavior and rhythmicity of mosquitoes, their abiotic and biotic interactions, disease vectors and mechanism of disease transmission. Chapters describe mosquito-borne human diseases, mosquito-borne veterinary diseases, and management of mosquitoes. This book provides the readers with both the positive as well as the negative aspects of mosquitoes. It also discusses their use in research as a model organism and development of micro needles and their role in crop pollination.
This book is useful for the students studying entomology, public health, medical and veterinary sciences, and applied life sciences. It is also a reference for those working in policy planning and vector management.
This book comprises works presented in the 1st International Conference of Geoscience, Remote Sensing, and Technology, which was held in Padang, Indonesia, in October 2023. It was hosted by the Center of Disaster Monitoring and Earth Observation, State University of Padang, Indonesia. Included are works related but not limited to geoscience, remote sensing, radar SAR, optic satellites, LiDAR, earthquakes, drones, geophysics, computer science, computer engineering, information technology, and mapping.
This book is dedicated to lightning transients and protection for renewable energy systems, including both wind and solar energy. In addition to the formation mechanism of lightning transients, the practical engineering application has also been addressed. This book is comprehensive and covers the methodology of electromagnetic transient modelling, electromagnetic coupling for PV system, lightning protection design, testing and evaluation. This book is particularly suitable for readers interested in lightning phenomena and renewable energy systems. It would benefit researchers, engineers and graduate students in the fields of electrical engineering, renewable energy, computational electromagnetism, etc.
This book focuses on reservoir surveillance and management, reservoir evaluation and dynamic description, reservoir production stimulation and EOR, ultra-tight reservoir, unconventional oil and gas resources technology, oil and gas well production testing, and geomechanics. This book is a compilation of selected papers from the 13th International Field Exploration and Development Conference (IFEDC 2023).
The conference not only provides a platform to exchanges experience, but also promotes the development of scientific research in oil and gas exploration and production. The main audience for the work includes reservoir engineer, geological engineer, enterprise managers, senior engineers as well as students.
