In this landmark work, the author team led by Dr. Sean Carroll presents the general principles of the genetic basis of morphological change through a synthesis of evolutionary biology with genetics and embryology. In this extensively revised second edition, the authors delve into the latest discoveries, incorporating new coverage of comparative genomics, molecular evolution of regulatory proteins and elements, and microevolution of animal development.
An accessible text, focusing on the most well-known genes, developmental processes and taxa. Builds logically from developmental genetics and regulatory mechanisms to evolution at different genetic morphological levels. Adds major insights from recent genome studies, new evo-devo biology research findings, and a new chapter on models of variation and divergence among closely related species. Provides in-depth focus on key concepts through well-developed case studies. Features clear, 4-color illustrations and photographs, chapter summaries, references and a glossary. Presents the research of Dr. Carroll, a pioneer in the field and the past president of the Society for Developmental Biology.
This anthology takes the ever-controversial discussion of pornography out of solely academic circles; it expands the questions about porn that academics might tackle and opens the conversation to those who know it best-the creators and users of porn. Features essays on non-traditional issues in porn, including celebrity sex tapes, virtual sex, S&M, homosexual porn, and technology's impact on the porn industry Features fascinating insights from psychologists, a lawyer, and an English professor, as well as industry insiders such as Dylan Ryder A fun, entertaining, and philosophically provocative approach to pornography, written for the general reader
Microsporidia: Pathogens of Opportunity provides a systematic overview of the biology of microsporidia. Written by leading experts in the field, the book combines background and basic information on microsporidia with descriptive methods and resources for working with the pathogen. Newly revised and updated for its second edition, Microsporidia will continue to be the standard text reference for these pathogenic protists, and is an indispensable research resource for biologists,
physicians and parasitologists. This new edition of this publication provides systematic reviews of the biology of this pathogen by leading experts in the field, and will be combined with descriptions of the methods and resources for working with this pathogen. o Provides a comprehensive summary of literature on microsporidia and microsporidiosis o The long-awaited update to the standard microsporidia reference text The Microsporidia and Microsporidiosis
o Written by an international team of authors representing each of the main research groups working on microsporidia o Chapters provide comprehensive overviews of general methodology as well as special techniques related to these organisms
The latest edition of this highly acclaimed textbook, provides a comprehensive and up-to-date overview of the science and medical applications of biopharmaceutical products. Biopharmaceuticals refers to pharmaceutical substances derived from biological sources, and increasingly, it is synonymous with 'newer' pharmaceutical substances derived from genetic engineering or hybridoma technology.
This superbly written review of the important areas of investigation in the field, covers drug production, plus the biochemical and molecular mechanisms of action together with the biotechnology of major biopharmaceutical types on the market or currently under development. There is also additional material reflecting both the technical advances in the area and detailed information on key topics such as the influence of genomics on drug discovery.
Practical Colonoscopy Jerome D. Waye, MD, Director of Endoscopic Education, Clinical Professor of Medicine, Mount
Sinai Medical Center, New York, NY, USA
James Aisenberg, MD, Clinical Professor of Medicine, Mount Sinai Medical Center, New York, NY,
USA
Peter H. Rubin, MD, Associate Clinical Professor of Medicine, Mount Sinai
Medical Center, New York, NY, USA Are you looking for a rapid-reference, step-by-step guide to teach you all that you need to know in order to perform high-quality colonoscopy? Then Practical Colonoscopy is the perfect resource for you. Drawing upon their collective century of experience performing and teaching colonoscopy, Drs. Waye, Aisenberg and Rubin share the "pearls" and principles that they find most useful in every day practice. The team is led by
Dr. Jerry Waye, one of the world's leading practitioners and teachers of endoscopy. Up-to-date, practical, clinically-focused, succinct and packed full of outstanding illustrations and videos, this multi-media tool guides you through the core aspects of best colonoscopy practice. Key features include: Lucid,step-by-step explanations of the techniques and principles that will help you to achieve outstanding results A companion website that contains 39 videos illustrating important techniques, findings, and problems Text-boxes that highlight and organize the pearls and pitfalls of colonoscopy practice Line diagrams that illustrate important strategies and maneuvers High-resolution still photographs that depict important findings and techniques GI trainees will find this the perfect introductory guide to colonoscopy, and more experienced specialists will value it as a refresher tool that is replete with hundreds of new pearls provided by world experts. Practical Colonoscopy is a must-have tool for today's colonoscopist.
Berto's highly readable and lucid guide introduces students and the interested reader to Gdel's celebrated Incompleteness Theorem, and discusses some of the most famous - and infamous - claims arising from Gdel's arguments. Offers a clear understanding of this difficult subject by presenting each of the key steps of the Theorem in separate chapters Discusses interpretations of the Theorem made by celebrated contemporary thinkers Sheds light on the wider extra-mathematical and philosophical implications of Gdel's theories Written in an accessible, non-technical style
Technogenarians investigates the older person?s experiences of health, illness, science, and technology. It presents a greater theoretical and empirical understanding of the biomedical aspects of aging bodies, minds, and emotions, and the rise of gerontechnology industries and professions. A unique scholarly investigation into elders as technology users Emphasizes the need to put aging, science, and technology in the center of analyses of health and illness Explores the rise of gerontechnology industries and professions Offers a critical study of the transformation of aging bodies, minds, and emotions into medical problems in need of medical solutions Combines two scholarly areas - Science and Technology Studies and the Sociology of Aging, Health, and Illness - to produce innovative scholarship
Clean root canal systems are essential for successful endodontic treatment. With contributions from leading endodontists from around the world, Dr. Nestor Cohenca here presents the etiology of endodontic disease caused by the endodontic biofilm and all therapies available to predictably disinfect the root canal system, thus increasing successful endodontic outcomes.
Disinfection of Root Canal Systems: The Treatment of Apical Periodontitis is an evidence-based manual that describes root canal anatomy, the endodontic biofilm, and the role of disinfection before presenting the most up-to-date methods of irrigation and disinfection. Individual chapters are devoted to each method, such as positive pressure irrigation, apical negative pressure irrigation, sonic activation, photodynamic therapy, laser technology, and ozonization and electrochemical activation. Clinical photographs throughout show proper irrigation and disinfection techniques.
Induced resistance offers the prospect of broad spectrum, long-lasting and potentially environmentally-benign disease and pest control in plants. Induced Resistance for Plant Defense 2e provides a comprehensive account of the subject, encompassing the underlying science and methodology, as well as research on application of the phenomenon in practice. The second edition of this important book includes updated coverage of cellular aspects of induced resistance, including signalling and defenses, costs and trade-offs associated with the expression of induced resistance, research aimed at integrating induced resistance into crop protection practice, and induced resistance from a commercial perspective. Current thinking on how beneficial microbes induce resistance in plants has been included in the second edition. The 14 chapters in this book have been written by internationally-respected researchers and edited by three editors with considerable experience of working on induced resistance. Like its predecessor, the second edition of Induced Resistance for Plant Defense will be of great interest to plant pathologists, plant cell and molecular biologists, agricultural scientists, crop protection specialists, and personnel in the agrochemical industry. All libraries in universities and research establishments where biological, agricultural, horticultural and forest sciences are studied and taught should have copies of this book on their shelves.
Filling a niche in the geomorphology teaching market, this introductory book is built around a 12 week course in fluvial geomorphology. `Reading the landscape' entails making sense of what a riverscape looks like, how it works, how it has evolved over time, and how alterations to one part of a catchment may have secondary consequences elsewhere, over different timeframes. These place-based field analyses are framed within their topographic, climatic and environmental context. Issues and principles presented in the first part of this book provide foundational understandings that underpin the approach to reading the landscape that is presented in the second half of the book. In reading the landscape, detective-style investigations and interpretations are tied to theoretical and conceptual principles to generate catchment-specific analyses of river character, behaviour and evolution, including responses to human disturbance. This book has been constructed as an introductory text on river landscapes, providing a bridge and/or companion to quantitatively-framed or modelled approaches to landscape analysis that are addressed elsewhere. Key principles outlined in the book emphasise the importance of complexity, contingency and emergence in interpreting the character, behaviour and evolution of any given system. The target audience is second and third year undergraduate students in geomorphology, hydrology, earth science and environmental science, as well as river practitioners who use geomorphic understandings to guide scientific and/or management applications. The primary focus of Kirstie and Gary's research and teaching entails the use of geomorphic principles as a tool with which to develop coherent scientific understandings of river systems, and the application of these understandings in management practice. Kirstie and Gary are co-developers of the River Styles® Framework and Short Course that is widely used in river management, decision-making and training. Additional resources for this book can be found at: www.wiley.com/go/fryirs/riversystems.
Stroke is a leading cause of disability and death Early and rapid diagnosis of stroke is essential for identifying the optimum treatment strategy. Recurrence can be prevented if the underlying mechanism is understood. The earlier appropriate rehabilitation programmes can be started, the better the chance of a strong recovery. Stroke provides the foundations for practice that will enhance your patient's chances of recovery. The expert authors provide the evidence-based roadmap you need to provide the best bedside care including: Bedside evaluation of the stroke patient Neurovascular imaging Treatment of acute ischemic stroke and hemorrhagic stroke Diagnosis of stroke mechanism and secondary prevention Post stroke recovery Telemedicine for the acute stroke patient Clinical in approach, practical in execution, Stroke will help you diagnose and manage your patients more effectively.
This book outlines a generic set of procedures, termed the River Styles Framework, which provides a set of tools for interpreting river character, behavior, condition, and recovery potential. Applications of the framework generate a coherent package of geomorphic information, providing a physical template for river rehabilitation activities.
management and restoration of rivers is a rapidly growing topic for environmental scientists, geologists and ecologists - this book provides a learning tool with which to approach geomorphic applications to river management
describes the essential geomorphological principles underlying river behaviour and evolution
demonstrates how the River Styles Framework can turn geomorphic theory into practice, to develop workable strategies for restoration and management
based on real case studies and authors extensive experience
applicable to river systems worldwide
synthesises fluvial geomorphology, ecology and management
This book comprehensively reviews the potential of focal therapy and discusses why the changing face of prostate cancer warrants a change in the way we treat men with the disease. It deals with the mechanisms by which disease can be localized within the gland and then the different technologies used for focal ablation. Bringing together eminent contributors in one accessible reference, this book introduces focal therapy to all urologists, oncologists, and radiologists who are involved in the treatment of men with prostate cancer.
How can prenatal testing help your patients? In utero diagnosis has undergone an amazing revolution in recent years. More tests are available; the indications for prenatal diagnosis have expanded - you can now advise your patients about disorders you could not have previously detected. Medical training for obstetricians, medical geneticists, and genetic counselors has not kept pace with these developments. Clinical exposure to common and unusual problems in prenatal diagnosis is limited. Prenatal Diagnosis: Clinical Cases and Challenges, based on the authors' several decades of experiences, fills this gap. Real cases portray diagnostic problems as a route to the underlying biology, the available testing options, and the results that might be obtained. The authors discuss the challenges of management, interpretation, and counseling. Cases used throughout emphasize three types of clinical problems: Chromosomal abnormalities Mendelian disorders Fetal structural abnormalities The decision to enter the world of prenatal diagnosis should be very carefully considered by any prospective mother. Prenatal Diagnosis: Clinical Cases and Challenges will help you discuss the issues in an informed manner with your patients.
Neuroanatomy and Neuroscience at a Glance provides a user-friendly introduction to the anatomy, biochemistry, physiology and pharmacology of the human nervous system within one, succinct, highly-illustrated volume. The double page spreads begin by summarising the anatomical structure and function of the different components of the central nervous system, followed by a section on applied neurobiology which outlines how to approach the patient with neurological and psychiatric problems and provides an overview of treatment and management options. Key features of this fourth edition include: A manageable overview of the structure and function of the central nervous system Full guidance on how to approach the patient with neurological problems and the investigations used in the most common scenarios Cases highlighting the clinical relevance of the basic neuroscience New chapters on the major neurotransmitters of the CNS and their functions, the enteric nervous system and stroke A fully updated companion website with interactive self-assessment questions and case studies, flashcards and revision notes at www.ataglanceseries.com/neuroscience Neuroanatomy and Neuroscience at a Glance is the ideal companion for anyone about to start a basic neuroanatomy or neuroscience course, or can be used as a refresher for those in clinical training.
The interrelationship between wild animal, domestic animals and human health is appreciated now more than ever before. This is because of the recognition of the involvement of wild animals in diseases of humans and domestic animals, the impact of disease on wildlife management and conservation biology, recognition of new forms of environmental contamination, and academic interest in disease as an ecological factor.
This is the first introductory level book about disease in wild animals that deals with basic subjects such as the nature of disease, what causes disease, how disease is described and measured, how diseases spread and persist and the effects of disease on individual animals and populations. In contrast to authors of many other veterinary books, Gary A. Wobeser takes a more general approach to health in wild animals, recognizing that disease is one ecological factor among many and that disease can never be considered satisfactorily in isolation. Rather than focus on individual causative agents and their effect on the individual animal, the emphasis is on why disease occurred, and on the complex interactions that occur among disease agents, the environment and host populations.
Written by a leading researcher in wildlife diseases, this book will fill a knowledge gap for those called to work with disease in wild animals who lack experience or training in the general features of disease as they relate to wild animals. Veterinarians, ecologists, wildlife biologists, population biologists and public health workers will find this book invaluable.
This pocket reference and revision guide is a must for all medical students and junior doctors preparing for major exams in clinical medicine or needing a rapid reminder of essential facts during a clinical attachment. Now thoroughly updated, this new edition combines the first editions of Rapid Medicine and Rapid Differential Diagnosis and contains reference to over 200 common medical conditions and diseases and 350 signs and symptoms encountered on a daily basis on the wards, in clinics and in exams. This concise, no-nonsense reference is presented in an A-Z format for easy access to information, and includes a thematic index with conditions sorted by speciality making it an ideal companion in any clinical situation.
This update to the award-winning The Origins of Modern Humans: A World Survey of the Fossil Evidence covers the most accepted common theories concerning the emergence of modern Homo sapiens?adding fresh insight from top young scholars on the key new discoveries of the past 25 years. The Origins of Modern Humans: Biology Reconsidered allows field leaders to discuss and assess the assemblage of hominid fossil material in each region of the world during the Pleistocene epoch. It features new fossil and molecular evidence, such as the evolutionary inferences drawn from assessments of modern humans and large segments of the Neandertal genome. It also addresses the impact of digital imagery and the more sophisticated morphometrics that have entered the analytical fray since 1984. Beginning with a thoughtful introduction by the authors on modern human origins, the book offers such insightful chapter contributions as: Africa: The Cradle of Modern People Crossroads of the Old World: Late Hominin Evolution in Western Asia A River Runs through It: Modern Human Origins in East Asia Perspectives on the Origins of Modern Australians Modern Human Origins in Central Europe The Makers of the Early Upper Paleolithic in Western Eurasia Neandertal Craniofacial Growth and Development and Its Relevance for Modern Human Origins Energetics and the Origin of Modern Humans Understanding Human Cranial Variation in Light of Modern Human Origins The Relevance of Archaic Genomes to Modern Human Origins The Process of Modern Human Origins: The Evolutionary and Demographic Changes Giving Rise to Modern Humans The Paleobiology of Modern Human Emergence Elegant and thought provoking, The Origins of Modern Humans: Biology Reconsidered is an ideal read for students, grad students, and professionals in human evolution and paleoanthropology.
This comprehensive resource for fellows/trainees and candidates for recertification in gastroenterology summarizes the field in a modern, fresh format. Prominent experts from around the globe write on their areas of expertise, and each chapter follows a uniform structure. The focus is on key knowledge, with the most important clinical facts highlighted in boxes. Color illustrations reinforce the text.
This highly illustrated, diagnostic guidebook provides a single comprehensive source of essential information to enable non-specialists to diagnose lymph node and related diseases with confidence. The text is didactic and practical, covering reactive as well as malignant conditions. Diagnosis of Lymphoproliferative Diseases approaches the disorders based on the WHO classification and is edited by members of the WHO panel for the classification of lymphomas. This second edition contains over 1000 high quality, digitised colour images and tables of essential criteria for each diagnosis. New features include: Full discussion of immunostaining, the core of modern diagnosis Variant forms and technical issues This authoritative guide is an essential reference for haematologists, haematopathologists, general pathologists, diagnostic histopathologists and oncologists.
Endoscopy is the primary diagnostic method for GI complaints and is replete with an ever expanding array of therapeutic capabilities. Successful Training in Gastrointestinal Endoscopy will provide all gastroenterologists with the exact set of skills required to perform endoscopy at the highest level. GI trainees will find it a crucial primer for learning endoscopy; teachers will find it a guide to understand how best to develop the expertise of their students; and experienced practicing gastroenterologists will find it a useful refresher tool to brush up on their existing endoscopic skills and to familiarise themselves with new procedures, including issues of safety and competence while performing them. With contributions from internationally recognized leaders in endoscopy education and an endorsement by the World Organisation of Digestive Endoscopy, each chapter will examine the specific skill sets and procedure related tasks which must be mastered when learning a particular technique, including: Specific descriptions of accessories required Standard training methods for the procedure Optimal utilization of novel learning modalities such as simulators Quality measures and objective parameters for competency Available tools for assessing competency once training has been completed In addition to the 400 high-quality, outstanding colour photos, the book will come with a DVD containing over 130 annotated teaching videos of both actual procedures and ex-vivo animal model simulations. These videos will illustrate, in a step by step fashion the proper techniques to be followed, highlighting clinical pearls from the experts and the most common mistakes to avoid. Successful Training in Gastrointestinal Endoscopy will be a key purchase for all gastroenterologists, whether in training or experienced, to allow them to develop and perfect their endoscopic skills. It will be a particularly useful guide for those interested in mastering the latest new techniques and procedures and an essential reference for teachers of endoscopy and students alike.
Note: DVD and other supplementary materials are not included as part of eBook file. These materials are available for download upon purchase.
Thermal processing remains the most important method of food preservation in use today, and the scale of the industry is immense. The large scale of these production operations makes it more important than ever that the process is performed perfectly every time: failure will lead to product deterioration and loss of sales at best, and at worst to serious illness or death. This volume is a definitive modern-day reference for all those involved in thermal processing. It covers all of the essential information regarding the preservation of food products by heat. It includes all types of food product, from those high in acid and given a mild heat process to the low-acid sterilised foods that require a full botulinum cook. Different chapters deal with the manufacturing steps from raw material microbiology, through various processing regimes, validation methods, packaging, incubation testing and spoilage incidents. The authors have extensive knowledge of heat preservation covering all parts of the world and represent organisations with formidable reputations in this field. This book is an essential resource for all scientists and technologists in the food manufacturing industry as well as researchers and students of food science and technology.
This fully revised and updated edition introduces the reader to sedimentology and stratigraphic principles, and provides tools for the interpretation of sediments and sedimentary rocks. The processes of formation, transport and deposition of sediment are considered and then applied to develop conceptual models for the full range of sedimentary environments, from deserts to deep seas and reefs to rivers.
Different approaches to using stratigraphic principles to date and correlate strata are also considered, in order to provide a comprehensive introduction to all aspects of sedimentology and stratigraphy. The text and figures are designed to be accessible to anyone completely new to the subject, and all of the illustrative material is provided in an accompanying CD-ROM. High-resolution versions of these images can also be downloaded from the companion website for this book at:
www.wiley.com/go/nicholssedimentology.
ebook (ePub) 88.57 €
